Wound Care

Infection Control and Promoting Healing

Besides the pain and reduced quality of life experienced as a result of acute and chronic wounds, their care and management also has a significant economic impact on health care providers.1

As knowledge of the wound healing process and causal effects of wound perpetuation grows, evidence implicates nitric oxide as being a key component.2 NO is known to control such processes as collagen deposition, angiogenesis and cellular proliferation. Impaired NO production is associated with slower healing and is linked to retarded healing experienced in diabetic ulcers.3

MOFgen products incorporated into wound dressings deliver controlled doses of nitric oxide to promote the natural healing mechanism, counteract the detrimental effects caused by reduced NO production and combat infection.

Potential benefits from delivering NO

  • Accelerate wound contraction and re-epithelialization
  • Improve the quality of the tissue in the healing wound
  • Increase blood flow to the wound site to increase nutrient supply
  • Prevent infection
  • Disperse and kill biofilms
  1. Guest JF, et al., BMJ Open, 2015;5: e009283. doi:10.1136/ bmjopen-2015-009283, Health economic burden that wounds impose on the National Health Service in the UK.
  2. Risk M, Witte M B and Barbul A, World J. Surg., 2004, 28, 301. Nitric Oxide and Wound Healing
  3. Schaffer M R et al., Surgery, 1997, 121, 513. Diabetes-Impaired Healing and Reduced Wound Nitric Oxide Synthesis: A Possible Pathophysiologic Correlation.